男，汉族，中共党员，博士研究生，教授，硕士生导师，北京农学院 生物与资源环境学院副院长。毕业于中国农业大学，农药学专业。国家公派法国国家科学研究院天然产物研究所联合培养博士。北京市青年教学名师。北京市农药学会第十一届、第十二届理事，北京农药学会青年工作委员会副主任委员，《农药学学报》青年编委，《Advanced Agrochem》青年编委，北京农学院优秀共产党员。
主要从事糖化学和天然产物化学的研究工作，具体包括寡糖合成方法学研究，农药、医药中间体的制备，天然活性化合物的合成，植物生长调节剂和果蔬保鲜剂的研发，纳米载药材料制备等。先后主持或完成国家十四五重点研发项目子课题、北京市自然基金面上项目、青年项目、市委组织部人才项目等国家级或省部级课题6项，其他项目5项。发表论文二十余篇。授权国家发明专利6项。主编出版国家林业与草业局十四五高等教育重点规划教材三部。作为副主编和编委出版7本国家级或省部级规划教材。主持承担教育部产学研协同育人项目1项，北京市高等教育学会课题面上项目1项，发表教改论文4篇，承担并完成教改课题2项，课程思政课题子课题1项。获得2013-2017年度北京农学院高等教育教学成果二等奖。2017-2021年度北京农学院高等教育教学成果二等奖（第一完成人）、一等奖（第六完成人）。指导学生获得省部级及以上奖项20余项。
主讲本科生普通化学、有机化学等课程。
主持或参加科研项目及人才计划项目情况（按时间倒序排序）：
1、十四五国家重点研发计划，重点专项“新机制和新功能植物生长调节剂创制与产业化”子课题：基于分子靶标的植物生长调节剂创制”，2024.1-2027.12
2、2023年度北京市自然科学基金面上项目,2232004,基于独角金内酯类似物的新型植物生长调节剂的设计、合成及生物活性研究.2023.1-2025.12
3、2019年北京市自然科学基金青年基金项目，2194072，基于底物类似物的新型氨基葡萄糖-6-磷酸合成酶抑制剂的设计、合成及生物活性研究，2194072，2019/01-2020/12
4、2018年金桥工程种子资金项目，基于底物类似物的新型几丁质酶抑制剂的设计、合成及活性研究
5、北京市教育委员会科技计划一般项目 ，SQKM201710020003，齐墩果酸三唑类衍生物作为新型酶抑制剂的研究，2017/01-2019/12
6、北京市委组织部项目，2014000020124G077，鼠李糖衍生物作为新型农药的设计、合成与活性研究、2015/04-2017/12。
7、大北农青年教师科研基金项目，14ZK008，基于活性寡糖分子的绿色农药创制研究，2015/01/-2017/12。
8、中国农业大学研究生科研专项，15051105、己糖胺酶抑制剂设计合成与活性研究、2011/04-2011/12、1.5万元、已结题、主持。
9、企事业委托横向项目，独角金内酯类似物的合成工艺研究，30万，主持。
近期发表的主要论文：
SCI论文：
1. Zhao Hanqing, Jia Huiqi, Duan Hongxia, Zhang Jianjun, Wang Daoquan, Liang Xiaomei. Synthesis of Two Tetrasaccharides Related to the O-Antigen from Azospirillum brasilense S17 and Azospirillum lipoferum SR65. Journal of Carbohydrate Chemistry, 2010, 29, 103-117.
2. Zhao Hanqing, Zong Guanghui, Zhang Jianjun, Wang Daoquan, Liang Xiaomei. Synthesis and Anti-Fungal Activity of Seven Oleanolic Acid Glycosides. Molecules, 2011, 16, 1113-1128.
3. Zhao Hanqing, Zhou Minjie, Duan Lifeng, Wang Wei, Zhang jianjun, Wang Daoquan, Liang Xiaomei. Efficient Synthesis and Anti-Fungal Activity of Oleanolic Acid Oxime Esters. Molecules, 2013, 18(3), 3615-3629.
4. GuanghuiZong, Hanqing Zhao, Rui Jiang, Jianjun Zhang, Xiaomei Liang, Baoju Li, Yanxia Shi, DaoquanWang. Design, Synthesis and Bioactivity of Novel Glycosylthiadiazole Derivatives. Molecules，2014, 19(6): 7832-7849.( parallel first authors)
5. Yan Jin, Hanqing Zhao, Huizhe Lu, Colleen M. Kuemmel, Jianjun Zhang, Daoquan Wang. Synthesis andHerbicidal Activity of Novel 1-(Diethoxy-phosphoryl)-3-(4-one-1H-1,2,3-triazol-1-yl)-propan-2-ylCarboxylic Esters., Molecules, 2015, 20(1): 1088-1103. (parallel first authors)
6. Hanqing Zhao, Minjie Zhou, Jianjun Zhang, Daoquan Wang, Xiaomei Liang, Yanhong Dong.Design, Synthesis, and Anti-fungal Activity of The Oleanic Acid Oxime Esters and Oxime ethers, 4th International Symposium on Pesticide and Environmental Safety Proceedings. 2012.
7. Zili Chen, Chen Xu, Hanqing Zhao*, Jianzhuang Zhao, Jianjun Zhang, Daoquan Wang. Design, Efficient Synthesis and Anti-Fungal Activity of Oleanolic Acid Derivatives. 5th International Symposium on Pesticide and Environmental Safety Proceedings of 4th International Workshop of Plant Protection Machinery and Application Techniques .2016
8. Boyang Hu, Hanqing Zhao*, Zili Chen, Chen Xu, Wenting Zhao, Jianzhuang Zhao, Synthes is and fungicidal activities of the oleanolic acid oxime ethers. Chinese Journal of Pesticide Science. 2017, 19(6): 0679-0687.
9. Boyang Hu, Hanqing Zhao *, Zili Chen, Chen Xu, Jianzhuang Zhao and Wenting Zhao. Effificient Synthesis and Bioactivity of Novel Triazole Derivatives. Molecules, 2018, 23(4), 709.
10. Zili Chen, Peixia Li, Weitong Liu, Zhe Zhuang, Yuanyuan Wu, Hanqing Zhao*, Jianjun Zhang*. High Efficiency Synthesis of the Tetrasccharide Repeating Unit in Azospirillum brasilense Strains Sp246 Based on Silica Gel Supported Perchloric Acid (HClO4-SiO2)[J]. Chinese Journal of Organic Chemistry, 2020, 40(6): 1716-1724.
11. Zili Chen†, Yu Jiang†, Chen Xu, Xiangyu Sun, Chao Ma, Zihao Xia* and Hanqing Zhao*. Oleanane-Type Triterpene Conjugates with 1H-1,2,3-Triazole Possessing of Fungicidal Activity[J]. Molecules, 2022, 27(15), 4928.
12. Yu Jiang, Wen-Hao Liu, Zi-Hao Xia,* and Han-Qing Zhao*.Transition-Metal-Free Multicomponent Reaction of Quinoxalinones with Alkenes and Zhdankin Reagent through Photoredox Catalysis. Eur. J. Org. Chem. 2022, e202201125.
13. Zihao Xia, Lisha Wu, Shiqiang Yan*, Hanqing Zhao*. Saccharin-catalyzed multicomponent cascade reactions for the synthesis of 1,2,3,4,6-pentasubstituted piperidines. J Heterocyclic Chem. 2023;1–6.
14. Bao-Yi Yu, Dan Wang, Gao-Sheng Zhu, Chao-Jun Wei, Yi Jia, Chun-Liang Song, Jun Cheng, Han-Qing Zhao*. Synthesis, crystal structure of four 1D to 3D coordination polymers as potential sensor for the detection of ions, antibiotics and pesticides in water media. Polyhedron. 2023, 230, 116242
15. Xiangkun Ran, Tian Sun, Runze Zhou, Chaojun Wei, Wa Gao* and Hanqing Zhao*. In situ formation of Cu2O decorated CuZnAl-layered double hydroxide heterostructured photocatalysts for enhancing the degradation of tetracycline under visible light. New J. Chem. 2023, 47, 2914
16. Wenhao Liu, Runjiao Liu, Xingyuan Liu, Hanqing Zhao*, Zihao Xia*. Metal-Free Synthesis of α-Iminonitriles via Visible Light Photoredox Catalysis. Asian Journal of Organic Chemistry. 2023, 20
17. Tian-Shi Jiang, Xin-Yu Li, Chang-Heng Zhu, Han-Qing Zhao, Bismuth selenide nanosheet layer materials with peroxidase activity for antimicrobial applications, Advanced Agrochem, 2024, ISSN 2773-2371, https://doi.org/10.1016/j.aac.2023.12.002.
18. Tian-shi Jiang, Su-zhen Qi, Chang-heng Zhu, Han-qing Zhao, Liu-sheng Duan, Reducing pesticide use: Synthesis and application of ROS-SPC as an efficient nanocarrier and scavenger of reactive oxygen species in plants, Advanced Agrochem, 2024, ISSN 2773-2371, https://doi.org/10.1016/j.aac.2024.03.001.
19. Yu Jiang, Chang-Heng Zhu, Zi-Hao Xia*, Han-Qing Zhao. Novel quinoxalinone-1,2,3-triazole derivatives as potential antifungal agents for plant anthrax disease: Design, synthesis, antifungal activity and SAR study. Advanced Agrochem. 2024.3.222-228.
20. Xiao-Yun Sun, Wen-Hao Liu, Xing-Yuan Liu, Wa Gao*, Han-Qing Zhao*, Zi-Hao Xia*. Self-photocatalyzed three-component radical cascade reaction of quinoxalinones, simple alkenes and zhdankin reagent. Molecular Catalys. 2024, 557, 113981. DOI：10.1016/j.mcat.2024.113981.
21. Wenhao Liu, Xingyuan Liu, Runjiao Liu, Hanqing Zhao*,Zihao Xia*. Self-Catalyzed, Visible-Light-Induced Selective C3-H Aroylation of Quinoxalin-2(1H)-ones with Arylaldehydes by Air as an Oxidant. J. Org. Chem. 2024, 89, 10, 7233–7242.
22. Zi-Ping Wang, Yu Wang, Xin-Yu Li, Lin-Fang Jia, Ai-Zhen Yang, Wen-Ting Zhao, Yi Jia, Bao-Yi Yu, Han-Qing Zhao. Water-stable mixed-ligand Cd(II) metal-organic frameworks as bis-color excited ffuorescent sensors for the detection of vitamins and pesticides in aqueous solutions. Journal of Molecular Structure. 2024, 1305, 137699.
中文期刊
1、 王伟成,李欣雨,赵汗青.葡萄糖噻唑类衍生物的合成及杀菌活性研究[J]. 现代农药, 2024, 23(02): 45-53.
2、 樊艳艳,李欣雨,李世豪,赵汗青. 糖基噻唑类衍生物的合成及其杀菌活性[J/OL]. 合成化学,2024. https://doi.org/10.15952/j.cnki.cjsc.1005-1511.23173.
3、 刘伟童,朱长恒,蒋禹,赵汗青. 香草醛异噁唑衍生物的设计合成及杀菌活性[J]. 化学试剂, 2024, 46(03): 16-23. DOI:10.13822/j.cnki.hxsj. 2023. 0677.
4、 李睿,曹月阳,刘郁枫,赵汗青, 赵文婷. 生物炭材料分散固相萃取环境水中有机氯农药[J]. 化学试剂, 2023, 45(08): 116-121. DOI:10.13822/j.cnki.hxsj.2023.0057.
5、 吉昱锟, 江天石, 齐素珍, 赵汗青*, 段留生*. 纳米三臂星形聚合物的设计合成及负载氟啶胺性能研究. 农药学学报, 2024, 05.
所得荣誉：
2015年北京市委组织部优秀人才（青年骨干个人）
2017年获得2013-2017年度北京农学院高等教育教学成果二等奖。（第六完成人）
2019年北京农学院优秀共产党员
2020年北京农学院三育人先进集体（团队负责人）
2020年获得北京市优秀本科毕业论文（指导教师）
2021年获得2017-2021年度北京农学院高等教育教学成果二等奖。（第一完成人）
2021年获得2017-2021年度北京农学院高等教育教学成果一等奖。（第六完成人）
2021年北京农学院优质本科课程（课程负责人）
2021年北京农学院课程思政示范课程（课程负责人）
2021经中共北京市教委批准，获北京高校第十二届青年教师教学基本功比赛优秀指导教师奖
2021年北京市先进班集体（班主任）
2022年北京农学院优质本科教材课件
2022年北京市优秀基层组织（班主任）
2022年北京高校优质本科教案《绿色化学》
2022年获得北京市优秀本科毕业论文（指导教师）
2023年北京农学院青年教学名师
2023年北京市青年教学名师
2024年北京高校优质本科教材《有机化学》
编写教材
十一五国家级规划教材
有机化学(第三版)高等教育出版社 ISBN 978-7-04-047332-2 参编
有机化学习题集(第三版)高等教育出版社 ISBN 978-7-04-047323-0 参编
有机化学实验(第三版)高等教育出版社 ISBN 978-7-04-047332-2副主编
十四五省部级重点规划教材：
有机化学 中国林业出版社 主编
有机化学习题集 中国林业出版社 主编
有机化学实验 中国林业出版社 主编
普通高等教育十三五规划教材
有机化学 中国林业出版社 ISBN 978-7-5038-9619-4 参编
有机化学习题集 中国林业出版社 ISBN 978-7-5038-9620-0 副主编
有机化学实验 中国林业出版社 ISBN 978-7-5038-9617-0参编
《普通化学实验》中国林业出版社，ISBN 978-7-5038-8565-5 参编
授权发明专利：
2019年，一种呋喃葡萄糖基三氮唑类化合物极其制备方法和杀菌剂，专利号： ZL201711326362.X（第一发明人）
2020年，齐墩果酸衍生物及制备方法、应用，专利号 ZL201711076134.1 （第一发明人）
2022年，糖基异噁唑类化合物及其制备方法和杀菌剂。专利号 ZL202011516634.4 （第一发明人）
2022年，香草醛异噁唑类化合物及其制备方法和应用。专利号 ZL202110494154.0 （第一发明人）
2023年，具有独脚金内酯活性的肟醚类化合物及其用途。专利号：ZL2021 11453236.7 （第一发明人）
2024年，一种硫醚类独脚金内酯衍生物及其制备方法与调节植物生长的应用专利号：ZL202210377956.8（第三发明人）
Curriculum Vitae
I. Personal information
Hanqing Zhao, Ph.D, Professor, master supervisor. Vice Dean of College of Bioscience and Resources Environment, PI of the Creation and Application of New Green Pesticides Direction, the College of Bioscience and Resources Environment, Beijing University of Agriculture (BUA).
Prof. Zhao is Beijing Young Teaching Master.
The directors of Beijing Pesticide Society, deputy director of Youth Working Committee of Beijing Pesticide Society, young editorial board of Chinese Journal of Pesticide Science, young editorial board of Advanced Agrochem,
II. Research interests
Mainly engaged in the research of carbohydrate chemistry and natural product chemistry, including the methodology of oligosaccharide synthesis, the preparation of pesticide and pharmaceutical intermediates, the synthesis of natural active compounds, the research and development of plant growth regulators and fruit and vegetable preservatives, the preparation of nano-drug-carrying materials, etc.
III. Research Projects
He has presided over more than 10 national, provincial and ministerial, and enterprise projects, among which the most important are:
1. National Key Research and Development Program of The Fourteenth Five-Year Plan(2023YFD1700600)
2. Natural Science Foundation of Beijing (No. 2232004).
3. Beijing Natural Science Foundation Youth Foundation, (No. 2194072).
4. General project of Science and Technology Program of Beijing Municipal Education Commission, (SQKM201710020003).
5. Project of Organization Department of Beijing Municipal Party Committee, (2014000020124G077).
IV. Major Achievements
(Ⅰ) Representative works
The 14th Five-year provincial and ministerial level key planning textbooks:
1. Organic Chemistry (Chief editor), China Forestry Press
2. Organic chemistry experiment (Chief editor), China Forestry Press
(Ⅱ) Representative papers
1. Zhao Hanqing, Jia Huiqi, Duan Hongxia, Zhang Jianjun, Wang Daoquan, Liang Xiaomei. Synthesis of Two Tetrasaccharides Related to the O-Antigen from Azospirillum brasilense S17 and Azospirillum lipoferum SR65. Journal of Carbohydrate Chemistry, 2010, 29, 103-117.
2. Zhao Hanqing, Zong Guanghui, Zhang Jianjun, Wang Daoquan, Liang Xiaomei. Synthesis and Anti-Fungal Activity of Seven Oleanolic Acid Glycosides. Molecules, 2011, 16, 1113-1128.
3. Zhao Hanqing, Zhou Minjie, Duan Lifeng, Wang Wei, Zhang jianjun, Wang Daoquan, Liang Xiaomei. Efficient Synthesis and Anti-Fungal Activity of Oleanolic Acid Oxime Esters. Molecules, 2013, 18(3), 3615-3629.
4. GuanghuiZong, Hanqing Zhao, Rui Jiang, Jianjun Zhang, Xiaomei Liang, Baoju Li, Yanxia Shi, DaoquanWang. Design, Synthesis and Bioactivity of Novel Glycosylthiadiazole Derivatives. Molecules，2014, 19(6): 7832-7849.( parallel first authors)
5. Yan Jin, Hanqing Zhao, Huizhe Lu, Colleen M. Kuemmel, Jianjun Zhang, Daoquan Wang. Synthesis andHerbicidal Activity of Novel 1-(Diethoxy-phosphoryl)-3-(4-one-1H-1,2,3-triazol-1-yl)-propan-2-ylCarboxylic Esters., Molecules, 2015, 20(1): 1088-1103. (parallel first authors)
6. Hanqing Zhao, Minjie Zhou, Jianjun Zhang, Daoquan Wang, Xiaomei Liang, Yanhong Dong. Design, Synthesis, and Anti-fungal Activity of The Oleanic Acid Oxime Esters and Oxime ethers, 4th International Symposium on Pesticide and Environmental Safety Proceedings. 2012.
7. Zili Chen, Chen Xu, Hanqing Zhao*, Jianzhuang Zhao, Jianjun Zhang, Daoquan Wang. Design, Efficient Synthesis and Anti-Fungal Activity of Oleanolic Acid Derivatives. 5th International Symposium on Pesticide and Environmental Safety Proceedings of 4th International Workshop of Plant Protection Machinery and Application Techniques. 2016
8. Boyang Hu, Hanqing Zhao*, Zili Chen, Chen Xu, Wenting Zhao, Jianzhuang Zhao, Synthes is and fungicidal activities of the oleanolic acid oxime ethers. Chinese Journal of Pesticide Science. 2017, 19(6): 0679-0687.
9. Boyang Hu, Hanqing Zhao *, Zili Chen, Chen Xu, Jianzhuang Zhao and Wenting Zhao. Effificient Synthesis and Bioactivity of Novel Triazole Derivatives. Molecules, 2018, 23(4), 709.
10. Zili Chen, Peixia Li, Weitong Liu, Zhe Zhuang, Yuanyuan Wu, Hanqing Zhao*, Jianjun Zhang*. High Efficiency Synthesis of the Tetrasccharide Repeating Unit in Azospirillum brasilense Strains Sp246 Based on Silica Gel Supported Perchloric Acid (HClO4-SiO2)[J]. Chinese Journal of Organic Chemistry, 2020, 40(6): 1716-1724.
11. Zili Chen†, Yu Jiang†, Chen Xu, Xiangyu Sun, Chao Ma, Zihao Xia* and Hanqing Zhao*. Oleanane-Type Triterpene Conjugates with 1H-1,2,3-Triazole Possessing of Fungicidal Activity[J]. Molecules, 2022, 27(15), 4928.
12. Yu Jiang, Wen-Hao Liu, Zi-Hao Xia,* and Han-Qing Zhao*.Transition-Metal-Free Multicomponent Reaction of Quinoxalinones with Alkenes and Zhdankin Reagent through Photoredox Catalysis. Eur. J. Org. Chem. 2022, e202201125.
13. Zihao Xia, Lisha Wu, Shiqiang Yan*, Hanqing Zhao*. Saccharin-catalyzed multicomponent cascade reactions for the synthesis of 1,2,3,4,6-pentasubstituted piperidines. J Heterocyclic Chem. 2023;1–6.
14. Bao-Yi Yu, Dan Wang, Gao-Sheng Zhu, Chao-Jun Wei, Yi Jia, Chun-Liang Song, Jun Cheng, Han-Qing Zhao*. Synthesis, crystal structure of four 1D to 3D coordination polymers as potential sensor for the detection of ions, antibiotics and pesticides in water media. Polyhedron. 2023, 230, 116242
15. Xiangkun Ran, Tian Sun, Runze Zhou, Chaojun Wei, Wa Gao* and Hanqing Zhao*. In situ formation of Cu2O decorated CuZnAl-layered double hydroxide heterostructured photocatalysts for enhancing the degradation of tetracycline under visible light. New J. Chem. 2023, 47, 2914
16. Wenhao Liu, Runjiao Liu, Xingyuan Liu, Hanqing Zhao*, Zihao Xia*. Metal-Free Synthesis of α-Iminonitriles via Visible Light Photoredox Catalysis. Asian Journal of Organic Chemistry. 2023, 20
17. Tian-Shi Jiang, Xin-Yu Li, Chang-Heng Zhu, Han-Qing Zhao, Bismuth selenide nanosheet layer materials with peroxidase activity for antimicrobial applications, Advanced Agrochem, 2024, ISSN 2773-2371, https://doi.org/10.1016/j.aac.2023.12.002.
18. Tian-shi Jiang, Su-zhen Qi, Chang-heng Zhu, Han-qing Zhao, Liu-sheng Duan, Reducing pesticide use: Synthesis and application of ROS-SPC as an efficient nanocarrier and scavenger of reactive oxygen species in plants, Advanced Agrochem, 2024, ISSN 2773-2371, https://doi.org/10.1016/j.aac.2024.03.001.
19. Yu Jiang, Chang-Heng Zhu, Zi-Hao Xia*, Han-Qing Zhao. Novel quinoxalinone-1,2,3-triazole derivatives as potential antifungal agents for plant anthrax disease: Design, synthesis, antifungal activity and SAR study. Advanced Agrochem. 2024.3.222-228
20. Xiao-Yun Sun, Wen-Hao Liu, Xing-Yuan Liu, Wa Gao*, Han-Qing Zhao*, Zi-Hao Xia*. Self-photocatalyzed three-component radical cascade reaction of quinoxalinones, simple alkenes and zhdankin reagent. Molecular catalys. 2024, 557, 113981. DOI：10.1016/j.mcat.2024.113981.
21. Wenhao Liu, Xingyuan Liu, Runjiao Liu, Hanqing Zhao*,Zihao Xia*. Self-Catalyzed, Visible-Light-Induced Selective C3-H Aroylation of Quinoxalin-2(1H)-ones with Arylaldehydes by Air as an Oxidant. J. Org. Chem. 2024, 89, 10, 7233–7242.
22. Zi-Ping Wang, Yu Wang, Xin-Yu Li, Lin-Fang Jia, Ai-Zhen Yang, Wen-Ting Zhao, Yi Jia, Bao-Yi Yu, Han-Qing Zhao. Water-stable mixed-ligand Cd(II) metal-organic frameworks as bis-color excited ffuorescent sensors for the detection of vitamins and pesticides in aqueous solutions. Journal of Molecular Structure. 2024, 1305, 137699
(Ⅲ) Authorized invention patent:
Patent No.: ZL201711326362.X (First Inventor)
Patent No.: ZL201711076134.1 (First Inventor)
Patent No.: ZL202011516634.4 (First Inventor)
Patent No.: ZL202110494154.0 (First Inventor)
Patent No.: ZL2021 11453236.7 (First Inventor)
Patent No.: ZL202210377956.8 (First Inventor)
V. Contact information
Postal address: College of Bioscience and Resources Environment, Beijing University of Agriculture, No. 7, Beinong Road, Huilongguan, Changping, Beijing, 102206
Contact number: 010-80795502
Email: zhaohanqingbua@163.com
