姓名：伊兆红
所在系室：生物工程
研究方向:哺乳动物早期胚胎发育过程中,母源效应因子的作用机制。2016-2018年获得“北京市自然基金面上项目”支持。2017-2018年获得“北京市教委科研计划”的支持。
邮箱：yizhaoh2009@163.com
教育经历：
1990-1997年就读于中国农业大学生物学院，获学士学位和硕士学位；
1997-2003年就读于日本群马大学医学部生理学系分子医学专业，获博士学位。
工作经历：
2003-2009年于美国国立卫生研究院（NIH）从事博士后研究。
2010-2014年于中国科学院生物物理研究所任副研究员。
2014年加入北京农学院生物技术与工程学院从事教学和科研工作。
代表作：
Liu W Wang F, Xu Q, Shi J, Zhang X, Lu X, Gao Z, Ma H, Zhao Z, Duan E, Gao F, Gao S*,Yi Z*, Li L*. BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis.Nature Communications. 2017 Jan 27; 8:14182. (IF, 12.1).
Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, Xiang Y, Liu W, Chen J*,Yi Z*, and Li L*. Trp-Asp (WD) repeat domain 1 is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation.Journal of Biological Chemistry. 2017 Jan 27; 292(4):1438-1448. (IF, 4.2)
Liu Y, Lu X, Shi J, Yu X, Zhang X, Zhu K,Yi Z, Duan E, Li L. BTG4 is a key regulator for maternal mRNA clearance during mouse early embryogenesis. .Journal of Molecular Cell Biology.2016 Aug; 8(4):366-8. (IF, 6.0).
Xu Q, Wang F, Xiang Y, Zhang X, Zhao Z, Gao Z, Liu W, Lu X, Liu Y, Yu X, Wang H, Huang J,Yi Z, Gao S, Li L. Maternal BCAS2 protects genomic integrity in mouse early embryonic development.Development. 2015 Nov 15; 142(22):3943-53. (IF, 5.8).
Yu X.,Yi Z., Gao Z, ChenX., Wang Z., ZhengP., ZhuM., SunQ., Dean J., Li L. The subcortical maternal complex controls symmetric division of mouse zygotes by regulating F-actin dynamics.Nat. Commun.2014 Sep 11; 5:4887. (IF, 11.5).
主讲课程：动物生物化学和免疫学。
Curriculum Vitae
Personal information
Zhaohong Yi, Ph.D., Associate Professor,
Supervisor of Master’s student
Dr. Yi studied at the College of Biology, China Agricultural University from 1990 to 1997 and obtained Bachelor's and Master's degrees. She subsequently pursued her studies in Molecular Medicine at the Department of Physiology, School of Medicine in Gunma University in Japan from 1997 to 2003 and obtained a Doctor of Philosophy degree. She engaged postdoctoral research at the National Institutes of Health (NIH) in United States from 2003 to 2009. From 2010 to 2014, he served as an associate professor in the Institute of Biophysics, Chinese Academy of Sciences. In 2014, she joined the faculty of the College of Bioscience and Resources environment (formerly known as the College of Biotechnology and Engineering) at Beijing University of Agricultural, where she has been engaged in teaching and research. Her main teaching courses include Animal Biochemistry and Animal Physiology.
Research interests：
We use knockout or transgenic mouse models, combined with molecular biology and cell biology approaches to investigate the molecular mechanisms of mammalian early embryonic development and gamete formation.
Research projects：
The regulation role of BCAS2 in mouse spermatogenesis, supported from 2016 to 2018 by the "Beijing Natural Science Foundation General Project".
The mechanism of maternal factor ZEBD3 in mouse early embryo development, supported from 2017 to 2018 by the "Beijing Municipal Education Commission Research Program".
Representative papers:
(1) Lu Xukun, Zhao Zhen-Ao, Wang Xiaoqing, Zhang Xiaoxin, Zhai Yanhua, Deng Wenbo, Yi Zhaohong, Li Lei. Whole-transcriptome splicing profiling of E7.5 mouse primary germ layers reveals frequent alternative promoter usage during mouse early embryogenesis. Biology Open, 2018, 7(3) ( co-corresponding author )
(2) Liu Wenbo, Wang Fengchao, Xu Qianhua, Shi Junchao, Zhang Xiaoxin, Lu Xukun, Zhao Zhen-Ao, Gao Zheng, Ma Huaixiao, Duan Enkui, Gao Fei, Gao Shaorong, Yi Zhaohong, Li Lei. BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis. Nature Communications, 2017, 8: 14182-14182 ( co-corresponding author )
(3) Xiao Yi, Ma Haixia, Wan Ping, Qin Dandan, Wang Xiaoxiao, Zhang Xiaoxin, Xiang Yunlong, Liu Wenbo, Chen Jiong, Yi Zhaohong, Li Lei. Trp-Asp (WD) Repeat Domain 1 is essential for mouse peri-implantation development and regulates Cofilin phosphorylation. Journal of Biological Chemistry, 2017, 292(4): 1438-1448 (co-corresponding author)
(4) Qin Dandan, Gao Zheng, Xiao Yi, Zhang Xiaoxin, Ma Haixia, Yu Xingjiang, Nie Xiaoqing, Fan Na, Wang Xiaoqing, Ouyang Yingchun, Sun Qing-Yuan, Yi Zhaohong, Li Lei. The subcortical maternal complex protein Nlrp4f is involved in cytoplasmic lattice formation and organelle distribution. Development, 2019, 146(20)
(5) Gao Zheng, Zhang Xiaoxin, Yu Xingjiang, Qin Dandan, Xiao Yi, Yu Yang, Xiang Yunlong, Nie Xiaoqing, Lu Xukun, Liu Wenbo, Yi Zhaohong, Li Lei. Zbed3 participates in the subcortical maternal complex and regulates the distribution of organelles. Journal of Molecular Cell Biology, 2018, 1(10): 74-88
Contact information
Postal address: College of Bioscience and Resources environment, Beijing University of Agriculture, No. 7, Beinong Road, Huilongguan, Changping, Beijing, 102206
Contact number: 010-87099115
Email: yizhaoh2009@163.com
